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武汉大学沈晓课题组2018年10月招聘有机化学博士后/科研助理/联合培养研究生

武汉大学高等研究院沈晓课题组,主要从事催化有机合成方法学和元素有机化学等领域的研究。招聘博士后/研究助理/联合培养研究生多名 (长期有效)。

PI简介请见课题组主页:http://xiaoshen.whu.edu.cn/

博士后
职位要求:
1)有机化学博士,有写作和发表英文科技论文经历。
2)有团队精神,工作踏实,有责任感,易沟通。
薪酬待遇:工资及福利待遇按国家博士后相关规定和武汉大学相关规定从优考虑,并根据工作业绩额外发放津贴(年薪15-30万);博士后工作出站后,可申请武汉大学固定编制教师岗位。

研究助理/联合培养研究生
职位要求:
1)本科或硕士学位,有机化学相关专业,熟悉常规有机化学实验技术和操作。
2)工作踏实,有责任感,具有良好的沟通能力和合作精神。
3)英语良好,能独立阅读英文文献。
薪酬待遇:将提供具有竞争力的薪酬待遇,并根据工作业绩额外发放津贴,可优先报考硕士或者博士研究生。

请发送个人简历、主要研究成果等相关资料到:xiaoshen@whu.edu.cn;并注明可到岗工作时间。

代表性论文:
1.        X. Shen, T. T. Nguyen, M. J. Koh, D. Xu, A. W. H. Speed, R. R. Schrock, A. H. Hoveyda. “Kinetically E-Selective Macrocyclic Ring-closing Metathesis” Nature 2017, 541, 380.
2.        C. Xu,* X. Shen,* A. H. Hoveyda. “In situ Methylene Capping: A General Strategy for Efficient Stereo-Retentive Catalytic Olefin Metathesis. The Concept, Methodological Implications and Applications to Synthesis of Biologically Active Compounds”  J. Am. Chem. Soc. 2017, 139, 10919. (*共同第一作者).
3.        F. Meng, X. Li, S. Torker, Y. Shi, X. Shen, Amir H. Hoveyda “Catalytic Enantioselective 1,6-Conjugate Additions of Propargyl and Allyl groups” Nature 2016, 537, 387.
4.        T. T. Nguyen, M. J. Koh, X. Shen, F. Romiti, R. R. Schrock, A. H. Hoveyda. “Kinetically Controlled E-Selective Catalytic Olefin Metathesis” Science 2016, 352, 569.
5.        X. Shen, C. N. Neumann, C. Kleinlein, N. W. Goldberg, T. Ritter. “Alkyl Aryl Ether Bond Formation with PhenoFluor” Angew. Chem. Int. Ed. 2015, 54, 5662.
6.        N. W. Goldberg, X. Shen, J. Li, T. Ritter “AlkylFluor: Deoxyfluorination of Alcohols” Org. Lett. 2016, 18, 6102.
7.        X. Shen, W. Miao, C. Ni, J. Hu. “Stereoselective Nucleophilic Fluoromethylation of Aryl Ketones: Dynamic Kinetic Resolution of Chiral α-Fluoro Carbanions” Angew. Chem. Int. Ed. 2014, 53, 775.
8.        X. Shen, W. Zhang, C. Ni, Y. Gu, J. Hu. “Tuning the Reactivity of Difluoromethyl Sulfoximines from Electrophilic to Nucleophilic: Stereoselective Nucleophilic Difluoromethylation of Aryl Ketones” J. Am. Chem. Soc. 2012, 134, 16999.
9.        X. Shen, W. Zhang, L. Zhang, T. Luo, X. Wan, Y. Gu, J. Hu. “Enantioselective Synthesis of Cyclopropanes That Contain Fluorinated Tertiary Stereogenic Carbon Centers: A Chiral α-Fluoro Carbanion Strategy” Angew. Chem. Int. Ed. 2012, 51, 6966.
10.        X. Shen, L. Zhang, Y. Zhao, L. Zhu, G. Li, J. Hu. “Nucleophilic Fluoromethylation of Aldehydes with Fluorobis(phenylsulfonyl)methane: The Importance of Strong LiO Coordination and Fluorine Substitution for CC Bond Formation” Angew. Chem. Int. Ed. 2011, 50, 2588.
11.        X. Shen, M. Zhou, C. Ni, W. Zhang, J. Hu. “Direct Monofluoromethylation of O-, S-, N-, and P-Nucleophiles with PhSO(NTs)CH2F: Accelerating Effect of α-Fluorine Substitution” Chem. Sci. 2014, 5, 117.
12.        X. Shen, Q. Liu, T. Luo, J. Hu. “Nucleophilic Difluoromethylation of Epoxides with PhSO(NTBS)CF2H by a Preorganization Strategy” Chem. Eur. J. 2014, 20, 6795.
13.        X. Shen, J. Hu. “Fluorinated Sulfoximines: Preparation, Reactions and Applications” Eur. J. Org. Chem. 2014, 4437.
14.        X. Shen, Q. Liu, W. Zhang, J. Hu. “Stereoselective Synthesis of (Sulfonimidoyl)cyclopropanes with (R)-PhSO(NTs)CH2Cl and α,β-Unsaturated Weinreb Amides: Tuning the of Selectivity between C–Cl and C–S Bond Cleavage” Eur. J. Org. Chem. 2016, 906.
15.        X. Shen, Q. Liu, C. Ni, J. Hu. “Nucleophilic Difluoro(phenylsulfonimidoyl)- methylation of Unactivated Alkyl Bromides with PhSO(NTBS)CF2H: Facile Entry into gem-Difluoroalkenes” Chin. J. Chem. 2014, 32, 703.
16.        X. Shen, C. Ni, J. Hu. “Highly Stereoselective and One-Pot Synthesis of Tetra-substituted Monofluoroalkenes with Aldehydes and Fluorobis(phenyl- sulfonyl)methane” Chin. J. Chem. 2013, 31, 878.
17.        X. Shen, C. Ni, J. Hu. “Nucleophilic Fluoroalkylation of α,β-Unsaturated Carbonyl Compounds with α-Fluorinated Sulfones: Investigation of the Rever-sibility of 1,2-Additions and the Formation of 1,4-Adducts” Helv. Chim. Acta, 2012, 95, 2043.
18.        Q. Liu, X. Shen, C. Ni, J. Hu. “Stereoselective Carbonyl Olefination with Fluorosulfoximines: Facile Access to Z or E Terminal Monofluoroalkenes” Angew. Chem. Int. Ed. 2017, 56, 619.
19.        T. Luo, R. Zhang, X. Shen, W. Zhang, C. Ni, J. Hu, “Brønsted acid-catalyzed 1,2-fluorine migration with fluoroepoxides” Dalton Trans. 2015, 44, 19636.
20.        T. Luo, R. Zhang, W. Zhang, X. Shen, T. Umemoto, J. Hu. “Divergent Rearrangements of Cyclopropyl-Substituted Fluoroepoxides Involving C–F Bond Cleavage and Formation” Org. Lett. 2014, 16, 888.
21.        Y. Zhao, C. Ni, F. Jiang, B. Gao, X. Shen, J. Hu. “Copper-Catalyzed Debenzoylative Monofluoromethylation of Aryl Iodides Assisted by the Removable (2-Pyridyl)sulfonyl Group” Acs Catal. 2013, 3, 631.

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